Neuroengineering

Neuroengineering is a discipline within biomedical engineering that uses engineering techniques to understand, repair, replace, enhance, or otherwise exploit the properties of neural systems. Neural engineers are uniquely qualified to solve design problems at the interface of living neural tissue and non-living constructs. Prominent goals in the field include restoration and augmentation of human function via direct interactions between the nervous system and artificial devices.

Much current research is focused on understanding the coding and processing of information in the sensory and motor systems, quantifying how this processing is altered in the pathological state, and how it can be manipulated through interactions with artificial devices including brain-computer interfaces and neuroprosthetics.

Other research concentrates more on investigation by experimentation, including the use of neural implants connected with external technology.

Assistant Professor
Research Interests:

Our lab studies the response of bacteria to antibiotics in order to develop new methods for eradicating persistent bacteria.  Bacterial persistence is a form antibiotic resistance in which a transient fraction of bacterial cells tolerates severe antibiotic treatment while the majority of the population is eliminated. These ‘persisters’ can contribute to chronic infections and are a major medical problem. Despite their medical and scientific importance, presistence is not fully understood. A crucial challenge in studying bacterial persistence results from a lack of methods to isolate persisters from the heterogeneous populations in which they occur. As a result, systems-level analysis of persisters is beyond current techniques, and fundamental questions regarding their physiological diversity remain unanswered. Our lab seeks to develop methods to isolate persisters and study them with systems-wide, molecular techniques.  The resulting findings will be used to engineer improved antibiotic therapies.  Dr. Allison’s previous research included development of a novel method to eradicate pathogenic bacteria, including Escherichia coli and Staphylococcus aureus, by metabolic stimulation and the finding that bacteria communicate with each other to alter their tolerance to antibiotics.

Research Areas:
Neuroengineering, Pharmaceuticals & Drug Delivery
Professor,
Research Interests: Digital signal processing for speech and audio enhancement Machine learning for audio Signal processing for the hearing impaired Ultra-low power signal processing systems Bio- and Neuro-inspired signal processing techniques and architectures
Research Areas:
Neuroengineering
Assistant Professor
Research Interests:

Therapeutic applications of ultrasound: Costas Arvanitis’ research investigates the therapeutic applications of ultrasound with an emphasis on brain cancer, and central nervous system disease and disorders. His research is focused on understanding the biological effects of ultrasound and acoustically induced microbubble oscillations (acoustic cavitation) and using them to study complex biological systems, such as the neurovascular network and the tumor microenvironment, with the goal of developing novel therapies for the treatment of cancer and central nervous system diseases and disorders.

Research Areas:
BioImaging, Biomechanics, Neuroengineering, Pharmaceuticals & Drug Delivery
Associate Professor
Research Interests:

Biomedical sensors and subsystems including bioMEMS Neural prostheses: cochlear and vestibular Vestibular rehabilitation

Research Areas:
Neuroengineering
Assistant Professor
Research Interests:

Diffuse optics, near infrared spectroscopy, diffuse correlation spectroscopy cerebral blood flow, cerebral oxygen metabolism, and hypoxia-ischemia. I am currently working on development and applications of a novel bedside monitor of cerebral oxygenation, perfusion, and metabolism. My goal is to apply these innovative optical techniques, dubbed near-infrared spectroscopy and diffuse correlation spectroscopy, to pediatric populations that could greatly benefit from a non-invasive, continuous monitor of brain health.

Research Areas:
BioImaging, Neuroengineering
Professor
Research Interests:

Neuromodulation of peripheral nerve activity Real-time control methods applied to electrophysiology measurements Autonomic modulation of visceral organs. Our laboratory combines engineering and neuroscience to tackle real-world problems. We utilize techniques including intracellular and extracellular electrophysiology, computational modeling, and real-time computing.  

Research Areas:
Neuroengineering
Professor
Research Areas:
BioImaging, Neuroengineering
Professor
Research Interests:

Dr. Chang is the director of the Comparative Neuromechanics Laboratory in the School of Applied Physiology. His research program focuses on trying to understand how animals move through and interact with their environment. He integrates approaches and techniques from both biomechanics and neurophysiology to elucidate both passive mechanical and active neural mechanisms that control limbed locomotion in humans and other terrestrial vertebrates. This multidisciplinary approach allows him to test hypotheses about the basic design and function of the locomotor apparatus throughout a variety of conditions. His current goal is to understand the extent to which muscular reflexes can influence limb coordination during locomotion and how global limb control strategies may be affected by sensorimotor perturbations.

Research Areas:
Biomechanics, Neuroengineering
Professor
Research Areas:
Medical Robotics, Neuroengineering
Assistant Professor
Research Areas:
BioImaging, Neuroengineering
Professor
Research Interests:

My research area is biomechanics and mechanobiology with focus on: Glaucoma, including studies of aqueous humour drainage, optic nerve head biomechanics, and stem cell therapies in glaucoma; and Mechanobiology of osteoarthritis.

Research Areas:
Biomechanics, Neuroengineering, Tissue Engineering & Regenerative Medicine
Research Scientist
Research Areas:
Biomechanics, Neuroengineering
Assistant Professor
Research Interests:

Magnetic resonance spectroscopy, brain thermometry, inflammatory biomarkers, and machine learning for neuroimaging. The focus of the Fleischer Biomedical Spectroscopy and Imaging Laboratory is the development of advanced imaging and spectroscopy tools for translational applications including identification of new biomarkers for monitoring cancer treatment and non-invasive brain thermometry. Our group is highly interdisciplinary and provides a collaborative and dynamic environment for students and trainees to conduct research with direct therapeutic and clinical applications.

Research Areas:
BioImaging, Neuroengineering
Associate Professor
Research Interests:

Neuroengineering, ultra-high throughput genomics instrumentation; detection, separation, amplification of DNA; 3-D microfabrication technologies for genomics applications; and micro-lenslet arrays.

Research Areas:
Biomechanics, Neuroengineering
MBNA Bowman Chair & Professor,
Research Interests:

Neuromodulation using multielecrode arrays, closed loop control theory, and optogenetics for epilepsy and movement disorders. Computational modeling of epilepsy networks for model-based and non-model based feedback control of optogenetic and electrical neuromodulation. Neurorestoration using gene and cell-therapy based approaches for degenerative and injury conditions. The Translational Neuroengineering Research Lab uses neuromodulation for epilepsy using a combination of the following advanced techniques: 1) Multimicroelectrode electrical stimulation using novel parameters informed by optimization of input/output relationships (both model- and non-model based MIMO) using closed-loop control theory including adaptive learning and machine learning approaches; 2) Optogenetic activation and inhibition using all forms of available channels including step-function opsins. These approaches identify novel brain regions that have more widespread control and targets specific cell types for activation and inhibiton. Closed loop control using multielecrode arrays informs and controls neuromodulation. 3) Hardware independent ‘luminopsins’: novel gene therapy approaches combining bioluminescent proteins with optogenetic channels for hardware independent, widespread and activity-regulatable neuromodulation. We use a combination of in vitro models, animal models (mouse, rat, non-human primate) and human patients undergoing epilepsy and deep brain stimulation surgery as our experimental models. In addition, the laboratory has developed novel gene therapy vectors for neurorestoration targeting key pivotal proteins regulating axon outgrowth in regenerative situations, including for Parkinson’s disease, spinal cord injury and retinal degeneration.

Research Areas:
Neuroengineering, Tissue Engineering & Regenerative Medicine
Assistant Professor
Research Interests:

Sensory physiology, neural circuits, cerebral cortex, computational neuroscience, neuroengineering, neural coding, optical imaging, and optogenetics. Bilal Haider’s research goal is to identify cellular and circuit mechanisms that modulate neuronal responsiveness in the cerebral cortex in vivo. He has identified excitatory and inhibitory mechanisms in vivo that mediate rapid initiation, sustenance, and termination of persistent activity in the cortex. He is investigating the role of inhibitory circuits during wakefulness. His work showed for the first time that synaptic inhibition powerfully controls the spatial and temporal properties of visual processing in the awake cortex. His future research will investigate mechanisms used by excitatory and inhibitory neuronal sub-types in the cortex during goal-directed behaviors.

Research Areas:
BioImaging, Neuroengineering
Assistant Professor
Research Interests:

Systems biophotonics: single-molecule biophotonics, super-resolution and advanced optical microscopy, imaging instrumentation and devices.

Research Areas:
BioImaging, Medical Robotics, Nanotechnology, Neuroengineering, Pharmaceuticals & Drug Delivery
Director of Translational Clinical Informatics
Assistant Professor
Research Areas:
BioImaging, Biomaterials, Biomechanics, Medical Robotics, Neuroengineering, Systems Biology
Professor,
Research Interests:

Magnetic resonance imaging, functional MRI, neural connectivity, learning and plasticity.

Research Areas:
BioImaging, Neuroengineering
Associate Professor
Research Interests:

Microphysiological systems (Organ-on-a-Chip), Theranostic nanomaterials (Nanomedicine), Biomaterials, Microfluidics, Controls

Research Areas:
Biomaterials, Nanotechnology, Neuroengineering, Pharmaceuticals & Drug Delivery, Tissue Engineering & Regenerative Medicine
Associate Professor
Research Interests:

Traumatic brain and spinal cord injury, Neural tissue engineering, Injury biomechanics, Neural interfacing, and Cognitive impairment associated with brain injury and aging.

Research Areas:
Biomechanics, Neuroengineering, Tissue Engineering & Regenerative Medicine
Director, BioEngineering Graduate Program
C.J. “Pete” Silas Endowed Chair and Professor
Research Interests:

Microfluidics; bioMEMS; behavior neuroscience; cell biology; automation and high throughput engineering approaches to biology and biotechnology.

Research Areas:
Nanotechnology, Neuroengineering, Stem Cell Engineering, Tissue Engineering & Regenerative Medicine
Assistant Professor
Research Interests:

Artificial intelligence, deep learning, reinforcement learning, computational and systems neuroscience, closed-loop neural interface systems, biomarker discovery and neuromodulation therapies for neuropsychiatric disorders such as epilepsy and Alzheimer's disease.

Research Areas:
Neuroengineering
Associate Professor
Research Interests:

We are interested in understanding the genetic basis of heritable behavioral variation. In the current age, it has become cheap and easy to catalog the set of genetic differences between two individuals. But which genetic differences are responsible for generating differences in innate behaviors, including liability to neurological diseases such as autism, bipolar disease, and schizophrenia? How do these causative genetic variants modify a nervous system? Besides their role in disease, genetic variation is the substrate for natural selection. To understand how behavior evolves, we must understand how it varies.

Research Areas:
Neuroengineering, Systems Biology
Assistant Professor
Research Interests:

The focus of our research is the mechanics of hearing. In order to improve our fundamental understanding of the biophysics of hearing, we develop multiphysics computational models of the mammalian ear and simulate the response of the inner ear (cochlea) and middle ear to sounds as well as the emission of sounds by the ear (otoacoustic emissions). This research could result in better diagnostic tools for hearing pathologies and in new treatments and devices that restore hearing.

Research Areas:
Biomechanics, Neuroengineering
Professor
Research Interests:

Mechanisms of motor coordination: role of sensory feedback for posture and locomotion, musculoskeletal biomechanics

Research Areas:
Biomaterials, Neuroengineering
Professor and Associate Chair of Faculty Development
Research Interests:

Dr. Pardue’s lab is focused on developing treatments for people with vision loss. Steps to successful treatment require understanding the mechanisms of the disease and characterizing temporal changes to identify therapeutic windows, with the ultimate goal of rehabilitation of visual function. She uses behavioral electrophysiological, morphological, molecular, and imaging approaches to evaluate changes in retinal function and structure. Her research is guided by applying knowledge of retinal circuits and visual processing, often leading to studies of cognition and the interaction of retinal and visual circuits during health and disease. Her studies start in animal models and move to human trials when possible. 

Research Areas:
Neuroengineering
Professor
Research Interests:

The major research focus of my research is on biomechanics and motor control of locomotion and reaching movements in normal as well as in neurological and musculoskeletal pathological conditions. In particular, we study the mechanisms of sensorimotor adaptation to novel motor task requirements caused by visual impairament, peripheral nerve or spinal cord injury, and amputation. We also investigate how motor practice and sensory information affect selections of adaptive motor strategies.

Research Areas:
Biomechanics, Neuroengineering, Systems Biology
Assistant Professor
Research Areas:
BioImaging, Neuroengineering
Professor
Research Interests:

Biological and computational vision; Theoretical and computational neuroscience; Signal processing and data analysis for biotechnology applications; Neuromodulation  

Research Areas:
Neuroengineering
Associate Professor
Research Areas:
Biomechanics, Neuroengineering, Tissue Engineering & Regenerative Medicine
Assistant Professor
Research Areas:
BioImaging, Biomaterials, Biomechanics, Nanotechnology, Neuroengineering
Associate Professor
Research Interests:

Physiological and biomechanical mechanisms underlying fine motor skills and their adjustments and adaptations to heightened sympathetic nerve activity, aging or inactivity, space flight or microgravity, neuromuscular fatigue, divided attention, and practice in humans. He uses state-of-the-art techniques in neuroscience, physiology, and biomechanics (e.g., TMS, EEG, fMRI, single motor unit recordings, microneurography, mechanomyography, ultrasound elastography, and exoskeleton robot) in identifying these mechanisms.

Research Areas:
Biomechanics, Neuroengineering
Assistant Professor
Research Areas:
Neuroengineering
Associate Professor,
Research Areas:
Biomechanics, Neuroengineering
Carol Ann and David D. Flanagan Professor
Research Interests:

Neural coding, neural signal processing, sensory processing, vision and touch, neural prosthetics, and estimation and control.

Research Areas:
Neuroengineering
Professor
Research Interests:

Biomechanics and neural control of movement, movement disorders, rehabilitation, musculoskeletal modeling, computational neuroscience, neuromechanical simulation of movement, and biorobotics.

Research Areas:
Biomechanics, Neuroengineering
Associate Professor
Research Areas:
Medical Robotics, Nanotechnology, Neuroengineering, Pharmaceuticals & Drug Delivery, Stem Cell Engineering, Tissue Engineering & Regenerative Medicine
Professor
Research Interests:

Focusing on biomedical computing and modeling such as biomedical informatics, bio-molecular and medical imaging data processing, data management and visualization, bio-molecular pathway modeling, and telemedicine.

Research Areas:
Biomechanics, Neuroengineering
Professor
Research Interests:

Disruptive technologies enabled by nanoscale materials and devices will define our future in the same way that microtechnology has done over the past several decades. Our current research centers on the design and synthesis of novel nanomaterials for a broad range of applications, including nanomedicine, regenerative medicine, cancer theranostics, tissue engineering, controlled release, catalysis, and fuel cell technology. We are design and synthesize/fabricate novel nanomaterials that could serve as: 1) theranostic agents for cancer and other diseases; 2) multifucntional probes for cellular tracking; 3) smart capsules for site-specific, on-demand delivery; and 4) scaffolds for the repair or regeneration of tissues.

Research Areas:
Nanotechnology, Neuroengineering, Tissue Engineering & Regenerative Medicine
Associate Professor,
Research Interests:

Our Computational Neuroethology Laboratory is interested in understanding how behaviorally-relevant sensory signals are encoded by cortical neurons, and what factors (e.g. experience, hormones) might lead to plastic changes in that code. We investigate this in the mouse, where ultrasonic communication between animals provides a natural behavioral context for these studies, and transgenic methods offer future possibilities for mechanistic dissection of coding mechanisms. Our experimental approaches include electrophysiology in awake mice, hormonal manipulations, immunohistochemistry, and behavioral analysis. We also employ computational methods to analyze the information processing capabilities of neurons.

Research Areas:
Neuroengineering
Research Areas:
BioImaging, Biomechanics, Medical Robotics, Nanotechnology, Neuroengineering
Research Interests:

Neuroengineering, Tissue Engineering, Organ-on-chips, Microfluidics, Drug Delivery, Cell Mechanics

Research Areas:
Nanotechnology, Neuroengineering, Tissue Engineering & Regenerative Medicine
Research Interests:

Hello I'm Philip, and I'm currently working for the IEN as the Biocleanroom Lab Manager, and Processing Engineer supporting the Integrated 3D systems Lab (Bakir) In my studies I'm pursuing a non-thesis BioE Masters Degree. Feel free to contact me about the Biocleanroom, BioE, or getting trained on tools in the Marcus Cleanrooms.

Research Areas:
Biomaterials, Nanotechnology, Neuroengineering, Pharmaceuticals & Drug Delivery
Research Areas:
BioImaging, Neuroengineering
Research Areas:
Neuroengineering
Research Areas:
Neuroengineering, Systems Biology
Research Interests:

Physiological sensing, neural engineering

Research Areas:
Neuroengineering
Associate Professor,
Research Interests:

Exploration of the coordination of skeletal muscle structure and function. This work has two thrusts: understanding the mechanism by which mechanical signals alter muscle structure and understanding the functional demands on muscle

Research Areas:
Tissue Engineering & Regenerative Medicine, Biomechanics, Neuroengineering
Research Areas:
Biomaterials, Neuroengineering, Pharmaceuticals & Drug Delivery, Stem Cell Engineering, Tissue Engineering & Regenerative Medicine
Research Areas:
Neuroengineering
Research Interests:

Auditory Cortex, Neural Characterization, Machine Learning

Research Areas:
Neuroengineering
Research Areas:
BioImaging, Neuroengineering
Research Areas:
Neuroengineering
Research Interests:

Neural signal processing

Research Areas:
Neuroengineering
Research Areas:
Neuroengineering
Research Areas:
BioImaging, Neuroengineering
Research Interests:

Scientific automation with a focus area in in-vivo patch clamping. Other interests include mechatronics, design, and computer modeling of thermal, electrical, mechanical, kinematic, and dynamic systems.

Research Areas:
Neuroengineering, Stem Cell Engineering
Research Areas:
Neuroengineering
Research Interests:

Microfludics, neuroscience, neuroengineering

Research Areas:
Neuroengineering
Research Areas:
Neuroengineering
BioE
Research Areas:
Neuroengineering
Research Areas:
Nanotechnology, Neuroengineering
Research Interests:

Autonomous, dynamic systems. Neuromechanics and human locomtion. Biomimetic controllers.

Research Areas:
Biomechanics, Neuroengineering
Research Areas:
BioImaging, Neuroengineering
Research Interests:

The intersection of computational neuroscience and machine learning, high-performance computing, distributed computing, and petabyte scaling algorithms.

Research Areas:
BioImaging, Biomechanics, Neuroengineering
Research Interests:

Connectomics, process optimization, electron microscopy, serial sectioning, microfluidics, capillary interactions, tomography

Research Areas:
Medical Robotics, Nanotechnology, Neuroengineering
Research Interests:

Neuroscience, robotics, and automation. 

Research Areas:
Biomechanics, Neuroengineering
Research Interests:

Neuroimaging, Neuroengineering, Deep Learning

Research Areas:
BioImaging, Neuroengineering
Research Interests:

Biomedical signal and image processing, Computational Neuroscience, Medical robotics

Research Areas:
BioImaging, Medical Robotics, Neuroengineering
Research Interests:

Biomedical Imaging / Image Processing Machine/Deep Learning Neuroengineering

Research Areas:
BioImaging, Neuroengineering
Research Interests:

We are investigating mild traumatic brain injury (mTBI) in a heterogeneous preclinical model, in order to capture the diversity of clinical mTBI patients.

Research Areas:
Neuroengineering
Research Interests:

My research interests involve rehabilition and assistive technologies for the augmentation and restoration of human mobility. 

Research Areas:
Medical Robotics, Biomechanics, Neuroengineering
Research Interests:

neural interfaces, functional electrical stimulation (FES), peripheral nerve stimulation, nerve conduction block, computational modeling, biochemistry, real-time system

Research Areas:
Neuroengineering
Research Areas:
Biomechanics, Neuroengineering
Research Areas:
Neuroengineering
Research Areas:
Biomechanics, Neuroengineering
Research Areas:
Neuroengineering
Research Areas:
Tissue Engineering & Regenerative Medicine, Neuroengineering, Pharmaceuticals & Drug Delivery
Research Interests:

Individuality, neural engineering, connecting brain and behavior

Research Areas:
Neuroengineering, Systems Biology
Bioengineering
Research Areas:
BioImaging, Biomechanics, Neuroengineering
Research Areas:
Nanotechnology, Neuroengineering, Biomaterials
Research Areas:
Biomechanics, Neuroengineering
Research Interests:

dynamics of the brain's intrinsic activity

Research Areas:
Neuroengineering
Ph.D. Student + R&D Engineer
Research Interests:

Neural Engineering + Biomaterials

Research Areas:
BioImaging, Medical Robotics, Tissue Engineering & Regenerative Medicine, Nanotechnology, Biomechanics, Neuroengineering, Pharmaceuticals & Drug Delivery, Stem Cell Engineering, Biomaterials
BioE
Research Areas:
Neuroengineering
Research Interests:

Electrophysiology Optogenetics Epilepsy

Research Areas:
Neuroengineering
Research Interests:

Regenerative medicine, aging, longevity, stem cell engineering, tissue engineering, neuroengineering

 

Research Areas:
Neuroengineering, Stem Cell Engineering, Tissue Engineering & Regenerative Medicine
Research Interests:

Space habitability, model-based systems engineering, neuroscience, cognitive engineering 

Research Areas:
Neuroengineering, Systems Biology
Assistant Professor
Research Areas:
BioImaging, Neuroengineering, Systems Biology
Associate Professor
Research Areas:
Biomaterials, Nanotechnology, Neuroengineering, Tissue Engineering & Regenerative Medicine
Assistant Professor
Research Areas:
BioImaging, Neuroengineering